脑心速通治疗冠心病心绞痛疗效观察

Treatment of angina pectoris in coronary heart disease with “nao xin su tong”(脑心速通):study of the rapeutic effectiveness

目的：观察脑心速通（大蒜素）治疗冠心病心绞痛的疗效。方法：采用组间对照及治疗前后自身对照的方法，观察了脑心速通治疗各型冠心病心绞痛２７例的临床疗效，同时设硝酸甘油治疗２２例为对照组。结果：脑心速通在总疗效、心电图缺血性ＳＴ段恢复和心肌耗氧量的改善方面与对照组相比，无显著性差异（治疗组、对照组的总有效率分别为８５．１９％和９０．９１％）。脑心速通的起效时间迟于硝酸甘油，但药后无副反应及用药时间短等特点优于硝酸甘油。结论：脑心速通有降低心肌耗氧量、改善心肌供血供氧作用，为一种新的治疗冠心病心绞痛药物。

Objective:To observe the clinical therapeutic effects of “nao xin su tong”(脑心速通) in treatment of angina pectoris in coronary heart disease.Methods:27 patients with angina pectoris were treated with “nao su xin tong” as treatment group,while 22 patients were treated with nitroglycerinum as control group,to compare two groups and selfcontrol before and after treatment.Results:It showed that there was no significant difference on the aspects of total therapeutic effect,recovery of ischemic change of ST segment in ECG and myocardial oxygen consumption between“nao xin su tong”and nitroglycerinum(The total curative rate of treatment group was 85 19%,while that of the control group was 90 91%).It needs longer time for presenting therapeutic effect of “nao xin su tong” than that of nitroglycerinum.On the other hand,“nao xin su tong”had less sideeffect and a shorter treatment course than nitroglycerinum.Conclusions:“Nao xin su tong”can reduce the volume of myocardial oxygen consumption and improve the blood and oxygen supplement for myocardium.