超敏C反应蛋白2种检测方法测定结果比较

Comparison of two methods for measuring high-sensitivity C-reactive protein

目的探讨乳胶凝集比浊法与速率散射比浊法测定超敏C反应蛋白(high-sensitivity YC-reactive protein,hsCRP)的相关性比较,及其含量在脑血管病患者中的变化的临床应用价值。方法采用乳胶凝集比浊法与速率散射比浊法同时测定hsCRP,正常对照组与急性脑血管病组共59例标本。结果乳胶凝集比浊法与速率散射比浊法检测结果阳性率分别为54·24%、47·46%,二者间无显著差异(P〉0.05);急性脑血管病组中hsCRP明显高于正常对照组(P<0.01)。结论乳胶凝集比浊法与速率散射比浊法检测hsCRP敏感性一致;hsCRP测定对急性脑血管病有明确的意义。

Objective To compare emulsion agglutination turbidimetric method and speed scattering turbidimetric method for determining serum level of high-sensitivity C-reactive protein（hsCRP）in cerebrovascular disease patients and the clinical relevance. Methods Both methods mentioned above were used simultaneously fordetermining serum level of hsCRP in 59example specimens collected fromcontrol group and acute cerebrovascular disease group. Results The positive rate of emulsion agglutination turbidimetric method and speed scattering turbidimetric method was 54.24% and 47.46% respectively; there was no significant difference（P〈0. 05） between the two methods; serum level of hsCRP was higher in acute cerebrovascular disease group than that in normal control group（P〈0.01）. Conclusion The sensitivity is consistent between the two methods in examining hsCRP;there is explicit significance in hs CRP determination to acute cerebrovascular disease .