静注尿激酶和肝素联合治疗急性脑梗塞

Acute cerebral infarction treated by Urokinase combined with Heparin intravenously

为了研究尿激酶、肝素联合治疗在急性脑梗塞治疗中的作用及效果,将急性脑梗塞患者78例,分为治疗组48例,给予尿激酶和肝素治疗;对照组30例,仅用甘露醇、能量和维脑路通治疗,分别在一天、一周、两周观察疗效。结果显示,治疗组显效率77.08％,在24小时内溶栓均有效,在12小时内溶栓有显著疗效,配合肝素治疗无一例出血与复发。对照组显效率43.33％,两组对比有显著差异。结果提示:脑梗塞急性期溶栓治疗疗效肯定,配合肝素能防止再梗塞,溶栓时间越早效果越好。

To study the effect of thrombolytic agents in the acute cerebral infarction (ACI), we observed 78 cases with ACI on Iday, I week and 2 weeks after the treatment, 48 cases treated by urokinase (UK) combined with heparin intravenously and 38 cases as controls. The results showed that the effective rate of treatment group was 77. 08% which was significantly higher than 43. 33% in controls CP<0. 01) and the patients treated by UK and heparin within 24 hours after the onset became better, especially within 12 hours. No recurrence and hemorrhage occured. This suggested the positive efect of thrombolytic treatment and prevention of reinfarction combined with heparin in the patients with ACI. The time using thrombolytic agents was earlier, the effect of treatment was better.