沐舒坦、爱喘乐持续气道湿化在颅脑损伤气管切开患者中的应用

Application of continuous humidification of airway on craniocerebrai injury patients with incision of trachea

目的探讨湿化气道的有效方法，以保证呼吸道通畅，降低脑损伤气管切开后呼吸道并发症。方法将82例颅脑损伤气管切开后患者随机分为2组，实验组采用沐舒坦、爱喘乐加入生理盐水持续气道内滴注，对照组采用传统方法（庆大霉素、糜蛋白酶、地塞米松加入生理盐水）持续气道内滴注，比较2种方法湿化气道的效果。结果沐舒坦、爱喘乐持续气道湿化在湿化程度、预防刺激性咳嗽、气道黏膜出血和肺部感染方面显著优于传统方法（P〈0．05）。结论沫舒坦、爱喘乐持续气道涅化法优于传统方法，能达到满意湿化，减少气道并发症的发生。

Objective To explore the modus operandi of airway humidification, so as to guarantee respiratory tract to be unobstructed and cut down respiratory tract complication of craniocerebral injury patients with incision of trachea. Methods 82 craniocerebral injury patients with incision of trachea were divided into two groups randomly. The experimental group received continuous intraairway instillation with Mucosolvi and Atrovent dissolved by normal saline, while the control group received continuous intraairway instillation with gentamicin, chymotrypsin, and hexadecadrol dissolved by normal saline, which was considered as routin method. The effectiveness of airway humidification was compared. Results There were significant difference in the level of humidification, prevention of irritable cough, hemorrhage of airway mucosa and pulmonary infection in experimental group compared with control group. Conclusions The method of continuous intraairway instillation with Mucosolvi and Atrovent dissolved by normal saline is better than routin method, which is helpful to reduce complication.