摘要
建立顶空毛细管气相色谱法测定头孢他美钠中的有机溶剂残留量.用HP-FFAP毛细管气相色谱柱,顶空进样法,FID检测器,以正丙醇为内标进行测定.乙醇、丙酮的线性范围分别为2.0-1000.0 mg·L^-1(r=0.9992),1.0-600.0 mg·L^-1(r=0.9994);乙醇、丙酮的平均回收率分别为100.3%、98.8%;RSD分别为2.2%、2.3%(n=5).本方法简单、准确、灵敏度高、重现性好,适用于头孢他美钠中有机溶剂残留量的测定.
The samples were injected into HP-FFAP capillary column by headspace sampler and analyzed with FID detector using n-propanol as the internal standard to develop headspace gas chromatography method for t of the residual organic solvents in cefetamet. The measurement results show as following: the linear ranges of ethanol and acetone were 2.0 - 1000.0 mg · L^-1( r =0.9992) ,1.0 -600.0 mg · L^-1( r =0.9994), respectively. The recoveries were 100.3% and 98.8% with RSD 2.2% and 2.3% ( n = 5 ), respectively. This experiment indicates the method is simple, accurate, and sensitive with good reproducibility. It can be used for the determination of the residual organic solvents in cefetamet.
出处
《海南大学学报(自然科学版)》
CAS
2007年第1期43-45,共3页
Natural Science Journal of Hainan University