代谢综合征体质因素的病例-对照研究

Constitution Factors for Metabolic Syndrome: A Case-control Study

目的进行代谢综合征相关体质因素研究。方法对代谢综合征和非代谢综合征者进行病例-对照研究,体质判定标准采用《中医体质分类判定标准》;代谢综合征诊断标准采用国际糖尿病联盟(IDF)于2005年颁布的定义。结果多元Logistic回归分析显示:在P<0.05水平,最终进入回归方程的相关体质因素有3个:平和质、痰湿质、湿热质,其中痰湿质、湿热质为代谢综合征发生的危险因素,且痰湿质在代谢综合征的发病中相对重要;平和质为保护因素。结论从体质角度探索代谢综合征的发病机制是对其病因病机研究的补充。

Objective To investigate the constitution factors for metabolic syndrome（MS）. Methods 271 MS cases and 271 non-MS controls were selected. They were assessed according to the diagnosis standard of constitution of TCM. Results Multiple logistic regression analysis revealed that phlegm-dampness constitution and dampness-heat constitution were dangerous factors for MS, norreal constitution was protective factor for MS （P〈0.05）. Conclusion Research on constitution play a role in investigating pathogenesis of MS.