1000美元基因组计划的可行性分析

Technical Feasibility of Sequencing a Mammalian Genome by ＄1000

通过对目前几种主要测序方法的分析,探讨了1 000美元测定哺乳动物全基因组序列计划的可行性。本研究认为以高保真酶介导的纳米级分子开关是解决1 000美金基因组计划的方案,或方案之一。

To reach the goal of $1000 for sequencing a mammalian genome, a variety of progresses have been obtained in the past years. The present paper discussed the pessibility of different strategies in approaching the goal of the $1000 genone project. The potential application of on/off switch in biochip sequencing is also discussed.