复方杏仁面膜治疗黄褐斑临床观察

Clinic study of almond cream in the treatment of chloasma

目的:观察复方杏仁面膜治疗黄褐斑的临床疗效。方法:选择女性黄褐斑患者148例,随机分为治疗组(86例)和对照组(62例)。治疗组外用复方杏仁面膜,每周2次,对照组外涂复方维A酸霜,每天1次,12周后对其疗效进行比较。结果:治疗组基本治愈36例,显效30例,有效率76.74%;对照组基本治愈17例,显效21例,有效率61.29%,两组比较差异有显著性(P<0.05)。结论:复方杏仁面膜能很好地抑制酪氨酸酶活性,减少黑素的合成,从而起到消除和减轻黄褐斑的作用,方法简单、使用方便,易于推广。

Objective To investigate the therapeutic effect of almond cream in the treatment of chloasma. Methods 148 female patients with chloasma were randomly divided into two groups. Treated group （n=86） received almond cream 2 times per week and control group （n=62） received tretinoin cream daily. After 12 weeks the curative effect were compared with two groups. Result The cure cases is 36 and the effective rate were 76.74% in treatment. There were significant differences between the treatment and control group （P〈0.05）. Conclusion The result suggest that almond cream is a simple convenient drug for chloasma because it can obviously restrain tyrosinase activity and reduce melanin synthesis.