重视中药的肝损伤问题

More emphasis and attention on liver injuries related to Chinese herbal medicine

根据目前为止的相关报道,中药所致的肝损伤占临床药物性肝损伤总病例的4．8%～32．6%。究其原因,除了没有遵照中医药辨证施治的基本要求,乱用、误用,成药制剂的制备工艺以及培植药材中农药的残留及品种混淆等外,中药本身的不良反应不可忽视。本文就常见致肝损伤的中药及其成分与致肝损害机制,中草药肝损害的临床特点及病理改变,中药致肝损伤的影响因素以及加强预防措施等方面作一概述。希望重视中草药的肝损伤问题,提高中医药服务人民健康的水平。

According to present status, liver injuries related to Chinese herbal medicine account for 4.8 %-32.6 % of total clinical drug induced liver injuries. The probable reasons may include unconformation to the basic Chinese traditional medicine rule of treating diseases with different syndromes, abusing and misusing herbs, craftwork problems during herb preparation, pesticide remain during herb plantation, and confusion of herb varieties. The toxin and side effects of Chinese herbs themselves should not be ignored. This article comprehended the commonly seen liver injuries caused by Chinese traditional herbs with its ingredients, mechanisms, clinical characteristics, and pathologic changes. Furthermore the influencing factors of the induced liver damage and the promotion of preventive measure should also be taken up at present in order to make sure of raising the serving standard for peoples＇ health.