加替沙星与左氧氟沙星治疗尿路感染80例临床对比分析

Comparative study of gatifloxacin and levofloxacin for urinary tract infection in 80 cases

目的:探讨加替沙星与左氧氟沙星治疗尿路感染的临床效果。方法:选择80例尿路感染患者,随机分为加替沙星组、左氧氟沙星组。两组分别用加替沙星0.2g/次,左氧氟沙星0.2g/次静脉滴注,均每日2次。疗程均为7～10天。结果:加替沙星组和左氧氟沙星组治疗尿路感染的有效率分别为97.5%,82.5%(P<0.05),细菌清除率分别为96.2%和84.3%(P<0.01);不良反应发生率分别为5%和7.5%。结论:加替沙星治疗尿路感染疗效确切、安全性高。

Objective：To evaluate the clinical efficacy and safety of gatifloxacin in the treatment of urinary tract infection.Methods： Eighty patients with urinary tract infection were randomly and equally divided to receive gatifloxacin（40cases） or levofloxaoin（40 cases）at 0.4 g/d for 7d or 14d in both groups.Results：The total effective rate of gatifloxacin group and levofloxacin group was 97.5% and 82.5% respetively （P〈0.05）, the bacterial clearance rate was 96.2% and 84.3%（P〈0.01） respectively.and the incidence of adverse reaction was 5% and 7.5%.respectively.Conclusion：Gatifloxacin is safe and effective for urinary tract infection.