2Sobue S, Nomura T, Ishikawa T, et al. Th1/Th2 cytokine profiles and their relationship to clinical features in patients with chronic hepatitis C virus infection [J]. J Gastroenterol, 2001, 36 (8) : 544-551.
3Gramenzi A, Andreone P, Loggi E, et al. Cytokine profile of peripheral blood mononuclear cells from patients with different outcomes of hepatitis C virus infection [J]. J Viral Hepat, 2005, 12 (5) : 525-530.
4Tsai SL,Liaw YF,Chen MH,et al. Detection of type 2-like T-helper cells in hepatitis C virus infection: implications for hepatitis C virus chronicity [J]. Hepatology, 1997, 25(2) : 449-458.
5Tseng CT, Klimpel GR. Binding of the hepatitis C virus envelope protein E2 to CD81 inhibits natural killer cell functions [J]. J Exp Med, 2002, 195(1): 43-49.
6Brady MT, MacDonald AJ, Rowan AG, et al. Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes [J]. Eur J Immunol, 2003, 33 (12) : 3448-3457.
7Wang JH, Layden TJ, Eekels DD. Modulation of the peripheral T-Cell response by CD40 mutants of hepatitis C virus: transition from a Th1 to a Th2 response [J]. Hum Immunol, 2003, 64(7) : 662-673.
8Jiao X, Wang RY, Feng Z, et al. DNA immunization encoding the secreted nonstructural protein 3 (NS3) of hepatitis C virus and enhancing the Th1 type immune response [J]. J Viral Hepat, 2004, 11(1): 18-26.
9Lazdina U, Huhgren C, Frelin L, et al. Humoral and CD4(+) T helper (Th) cell responses to the hepatitis C virus non-structural 3 (NS3) protein: NS3 primes Th1-like responses more effectively as a DNA-based immunogen than as a recombinant protein [J]. J Gen Virol, 2001, 82(Pt 6): 1299-1308.
10Jiao X, Wang RY, Feng Z, et al. Modulation of cellular immune response against hepatitis C virus nonstructural protein 3 by cationic liposome encapsulated DNA immunization [J]. Hepatology, 2003, 37(2): 452-460.
二级参考文献8
1Woitas R P，AIDS，1999年，13卷，11期，1313页
2Eckels D D，Human Immunol，1999年，60卷，3期，187页
3Chien D Y，J Clin Microbiol，1999年，37卷，5期，1393页
4Fan X G，Mediat Inflamm，1998年，7卷，4期，295页
5Ferrari C，Recent Results Cancer Res，1998年，154卷，2期，330页
