晚期皮肤鳞癌放疗配合外用顺铂增敏23例

Therapeutic Observation to Skin Scale Cancer Treated with Radio-Chemical Therapy Combined with External Shun Platinum Enhanced Sensitivity

[目的]探讨晚期皮肤鳞癌有效治疗方法。[方法]对晚期皮肤鳞癌23例,采用放疗配合外用顺铂治疗,观察临床疗效及毒副。[结果]完全缓解5例,部分缓解16例,稳定2例,总有效率为91·3%;毒副反应:白细胞减少4例,皮肤急性反应13例。[结论]局部晚期皮肤鳞癌,尤其是表面破溃的肿瘤,给予低密度顺铂外用配合放疗。提高局部治疗效果又不增加毒副作用。

[Objective] To explore effective method for later skin scale cancer. [Method] Apply radio-chemical therapy combined Shun Platinum to 23 cases of said disease, observe clinical effect and toxic and side effects. [Result] 5 eases were completely reiieved, 16 partly relieved, 2 stable, the total effective rate 91.3 % ; toxic and side effects; 4 cases reduced white ceils, 13 acute skin reaction. [Conclusion] For the local later skin scale cancer, esp. the cancer ulceration in the skin surface, to take low-density Shun Platinum combined with radio- chemical therapy can improve local treatment, meanwhile without increasing toxic or side effects.