超声引导下局部注射MTX治疗有心搏异位妊娠的疗效分析

Clinical Effect of Local Sonographically Guided Injection of Methotrexate on Ectopic Pregnancy with Fetal Cardiac Activity

[目的]研究超声引导下局部注射MTX治疗有心搏异位妊娠的疗效。[方法]25例有胎心搏动的异位妊娠为研究组,以43例无胎心搏动的异位妊娠为对照组,研究组采用阴道超声引导下局部注射MTX同时结合全身用药,对照组仅全身治疗肌肉注射MTX。[结果]研究组与对照组治疗成功率无显著性差异。而研究组治疗前血HCG明显高于对照组。[结论]对有胎心搏动的异位妊娠,超声引导下局部注射MTX结合全身用药疗效较好。

[Objective] To investigate an effective drug therapy for ectopic pregnancy with fetal cardiac activity. [Method] The study group included 25 patients with ectopic pregnancy and fetal cardiac activity, treated by combined local sonographically guided and systemic injection of methotrexate. The outcome of these patients was compared with the outcome of 43 patients who had ectopic pregnancy without fetal cardiac activity and were being treated only by systemic injection of methotrexate. [Result] There was no significant difference between the two groups comparing the success rate. Conversely, the initial HCG in study group was significantly higher than that in control group. [Conclusion] The combined local sonographically guided and systemic injection of methotrexate is associated with a successful outcome in patients with ectopic pregnancy and fetal cardiac activity.