骨髓基质干细胞治疗股骨头坏死的研究和应用

The Study and Application on MSCs in the Therapy of Osteonecrosis of the Femoral Head

综述了近年来骨髓基质干细胞(bone marrow mesenchymal stem cells,MSCs)在股骨头坏死领域的研究。对MSCs的生物学特性、分离与培养及成骨特性三方面内容进行论述,揭示MSCs的内在特性,说明其有潜力治疗骨坏死疾病;对MSCs治疗股骨头坏死临床运用的论述,说明MSCs治疗骨坏死疾病的可行性;并分析展望骨髓基质干细胞在应用上存在的问题及今后所要解决的难点。

There is a summary for the study of MSCs in the area of osteonecrosis of the femoral head. It discusses the bionomics, isolation and culture, and osteogenesis of MSCs to expose its internal character, which has the potentiality to treat the osteonecrosis; Through the discussion of clinical application of MSCs in treating osteonecrosis of the femoral head, it provides the feasibility to treat the osteonecrosis with MSCs. At last, it analyzes and prospects the problems, which would be faced in the near future.