某高校大学生泌尿生殖道支原体感染状况的调查及其影响因素分析

Prevalence and risk factors for the genitourinary tract infection by Mycoplasma in university students

目的通过对大学生泌尿生殖道支原体的检测,了解大学生泌尿生殖道支原体的感染状况.并分析影响大学生泌尿生殖道支原体感染的流行病学因素,为大学生泌尿生殖道支原体的预防提供科学依据。方法以某高校医学院2005级学生为研究对象,进行2次调查。按文献制备支原体培养基,取研究对象的中段尿,利用解脲脲原体和人型支原体在生长过程中分别水解尿素和精氨酸产生氨而使培养基变碱,从而使培养基由桔黄色变为紫红色而判断为阳性,2次均为阳性者才算为真阳性。同时采用问卷调查研究对象的基本情况和可能的影响因素,数据库建立和统计学分析采用SPSS 13.0,2χ检验用于单因素分析,成组Logistic回归分析用于多因素分析。结果共检测了998例大学生的尿标本,65例为阳性,其中女性54例,男性11例,总阳性率为6.51%。经单因素2χ检验,发现性别和是否会游泳与泌尿生殖道支原体的感染有关,经多因素成组Logistic回归分析,发现性别、父母健在情况和家庭居住地与泌尿生殖道支原体的感染有关。结论大学生人群存在泌尿生殖道支原体感染,并且女性感染率明显高于男性。父母健在情况、家庭居住地是影响大学生泌尿生殖道支原体感染的危险因素。

Objective To investigate the infection status of genitourinary tract mycoplasma in the undergraduate smaents, and to analyse the risx factors for gentournary tract mycoplasma infection,in order to provide the scientific theoretical basis of prevention against genitourinary tract mycoplasma infection in universities. Methods Questionnaire was made in order to investigate the risk factor for genitourinary tract mycoplasma infection. The objects included all students of grade 2005 in the medical college of a university. 500 μl middle urine of objects was taken into the culture medium that was made by ourselves. The result was judged according to the color change of the culture. Those whose urine in the culture became red were positive（＋）. Others were negative（-）. Every object was tested two times. Only those who were positive for two times were really positive. SPSS 13.00 was applied to statistical analysis.χ2 test was used for single factor analysis, Group Logistic Regression analysis was used for multiple factor analysis. Results 65 cases among 998 undergraduate students were mycoplasma infection positive （54 female, 11 male） , and the infection rate was 6.51%. Gender and swimming was found related to genitourinary tract mycoplasma infection after single factor analysis. Group Logistic regression analysis showed that sex, parents to be alive or not and family residence are risk factors. Conclusions There exists genitourinary tract mycoplasma infection in undergraduate students,and the infection rate of female is significantly higher than that of male. Gender,Parents to be alive or not and family residence are risk factors for genitourinary tract mycoplasma infection in university students.