艾迪注射液对白血病患者化疗后造血功能及肠道菌群影响的研究

The therapeutic action of AM injection for the function of hematopoiesis and disordered intestinal flora after leukemia chemotherapy

目的艾迪注射液可促进骨髓造血,扶植肠道正常菌群生长。方法将选择病例随机分为艾迪注射液治疗组(试验组)及常规化疗组(对照组)。观察其化疗前及化疗后2周IL-3及GM-CSF水平,外周血中性粒细胞绝对值,肠道常驻菌(肠杆菌、肠球菌、双歧杆菌、乳酸杆菌)指标。结果各项指标同单纯化疗组相比,差异均有显著性(P<0.05或P<0.01)。结论艾迪注射液具有促进骨髓造血功能、扶植肠道正常菌群生长的作用。

Objective AiDi injection could improve the function of hematopoiesis, prop up the growth of normal intestinal flora. Methods To devide the patients randonly into two groups：AiDi injection during chemotherapy（ experimental group） and chemotherapy only（ Control group）. The following data must be measured two weeks before and after chemotherapy ：the level of IL-3 and GM-CSF, peripheral mature neutrophilic granulocyte count. Intestinal permanent flora（ Enterobacteria,Enterococcus ,Btfidobacterrim and Lactobacillea）. Result All data showed remarkable differentce compared with the simple chemotheraphy group（ P 〈 0.05 or P 〈 0.01 ）. Conclusion AiDi injection can perform the function of improving the hematopoietic function and propping up the growth of nomal intestinal flora indeed.