26217例乙肝病毒血清标志物表达模式的探讨

Analysis of serological markers hepatitis virus for 26217

目的:探讨北京市大兴区人民医院2003年1月-2006年12月就诊人群的乙肝病毒(HBV)血清标志物的表达模式。方法:采用ELISA法对日常工作中的26 217份血清标本进行乙肝病毒表面抗原(HBsAg)、乙肝病毒表面抗体(HB-sAb)、乙肝病毒e抗原(HBeAg)、乙肝病毒e抗体(HBeAb)、乙肝病毒核心抗体(HBcAb)的检测。结果:共有9种模式,HBsAg阳性有4种模式,占48.43%;HBsAb阳性有3种模式,占40.82%;HBeAg阳性有2种模式,占16.72%;HBeAb阳性有4种模式,占25.79%;HBcAb阳性有7种模式,占81.01%。结论:加强宣传教育,普及知识,强化免疫仍是降低乙肝发病率的重要措施。

Objectives：To analyze the results of serological marker models of Hepatitis B virus patients, Methods：26 217 samples obtained from routine work in clinical laboratory had been detected by ELISA. Results： All of tested samples were divided into 9 different models, HBsAg positive groups have 4 models, occupied 48.43% ; HBsAb positive groups have 3 models, occupied 40. 82% ;HBeAg, HBeAb and HBcAb positive groups have 2,4 and 7 models,it occupied 16. 72% ,25.79% and 81.01% respectively. Conclusion ： Great attention should be paid to health education so as to prevent and control the occurrence of Hepatitis B virul. Strengthen the vaccination of the population in endemic areas was the most effective measures.