北京地区13336例成人空腹血脂水平分析

The analysis of serum lipids of 13 336 adults in Beijing

目的通过检测健康查体者空腹血脂水平来了解北京地区人群血脂水平现状及其血脂异常患病率。方法应用日立7 170全自动生化分析仪检测北京地区13 336例成人空腹血脂,血脂指标包括甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C),比较不同性别和年龄组间血脂水平差别及血脂异常患病率的差异。结果总体血脂异常患病率59.9%,男性71_6%,女性47.2%。男性 TC 平均(4.89±0.87)mmol/L、LDL-C 平均(3.33±0.84)mmol/L、HDL-C平均(1.28±0.30)mmol/L、TG 中位数1.32 mmol/L;女性 TC 平均(4.79±0.94)mmol/L、LDL-C平均(2.99±0.89)mmoL/L、HDL-C 平均(1.53±0.34)mmoVL、TG 中位数0.9mmol/L。男性和女性4种血脂成分异常患病率均随年龄增加而增高(P<0.01)。TC、LDL-C、TG 水平随年龄增加而增高(P<0.01),HDL-C 水平随年龄的增加有降低趋势(P<0.01)。TC 在25～44岁问男性高于女性(P<0.01),在55岁以上女性显著高于男性(P<0.05)。LDL-C 在18～44岁间男性高于女性(P<0.01),在45～74岁女性显著高于男性(P<0.01)。HDL-C 水平各年龄组女性明显高于男性(P<0.01)。TG 在18～54岁男性显著高于女性(P<0.01),在55～64岁组两性间无差异,64岁以上女性高于男性(P<0.05)。结论北京地区成人中血脂异常患病率较高,并且随年龄增大而增高,男女性别间血脂异常患病率差异有统计学意义。

Objective To evaluate the status of the morbidity of serum lipids in Beijing through the detection of serum lipids in health checking adults. Methods The serum total cholesterol （ TC ） , low density lipoprotein cholesterol （LDL-C）, high density lipoprotein cholesterol （HDL-C） and triglyceride （TG） were detected by chemistry test in 13 336 adults, and age-adjusted prevalence of dyslipidemia and its distribution in different sexes and age groups were statistically analyzed. Results The prevalence of total dyslipidemia is 59.9% , 71.6 % in male and 47.2% in female. The prevalence of the four components of serum lipids raised with age in both sex（ P 〈 0. 01 ）. TC,LDL-C,TG raised with age （ P 〈 0. 01 ） , HDL-C decreased with age （P 〈0. 01）o TC was higher in male than that in female among 25 -44 years old adluts （ P 〈 0. 01 ）, and TC was higher in female in more than 55 years adults （ P 〈 0. 05 ） . LDL-C was higher in male among 18 -44 years old adluts（P 〈0. 01 ） ,and TC was higher in female in more than 45 years adults （P 〈0. 01 ）. LDL-C was higher in male among 18 -44 years old adluts（ P 〈 0. 01 ）, and it was higher in female among 45 -74 years adults（P 〈0. 01 ） . HDL-C was higher in female in all age groups（P 〈0. 01 ）. TG was higher in male than that in female among 18 - 44 years old adluts （ P 〈 0. 01 ）, there was no difference between sexes among 55 -64 years old adluts,and it was higher in female in more than 64 years adults（ P 〈 0. 05 ）. Conclusion The prevalence of dyslipidemia was high in Beijing, and it increased with age ; there were differences of dyslipidemia between the two sexes.