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同源盒基因在急性髓系白血病中的表达 被引量:1

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摘要 同源盒基因(homeobox genes)最初发现于果蝇体内,以包含一段被称为同源盒的183bp的保守序列为特征。按照基因的同源性可将人类同源盒基因分为两类:Ⅰ类同源盒基因,又称HOX基因,分A、B、C、D4簇,依次位于人类7、17、12及2号染色体上。Ⅱ类同源盒分枝基因,又称Non-HOX基因,包括三氨基酸环延伸(three-amino-acid extension,TALE)家族(含MEIS家族及PBX家族)、OCT家族、HOX11等。
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2007年第5期559-561,共3页 Chinese Journal of Laboratory Medicine
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