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I型胶原吡啶交联终肽(ICTP)在骨肿瘤鉴别诊断中的意义 被引量:5

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摘要 目的检测原发性恶性骨肿瘤、骨转移性肿瘤患者血清中的I型胶原吡啶交联终肽(ICTP)活性,以评价ICTP在骨肿瘤诊断和鉴别诊断中的意义。方法对2004年本院骨肿瘤科收治的40例恶性骨肿瘤、14例骨转移性肿瘤患者,采用酶免疫测定(EIA)方法测定ICTP活性。结果恶性骨肿瘤组的ICTP活性为(16.33±11.82)μg/L,与健康对照组比较有统计学差异(P<0.01)。而骨转移性肿瘤组ICTP活性为(8.97±6.08)μg/L与对照组相比无统计学意义(P>0.05)。两组骨肿瘤组间也有统计学意义(P<0.05)。结论血清ICTP是反映骨肿瘤骨代谢的一个灵敏而简便的检测指标,并对骨肿瘤的诊断及鉴别诊断具有一定的临床意义。
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2007年第4期379-380,共2页 Chinese Journal of Cellular and Molecular Immunology
基金 北京市卫生局科学研究项目(2004-局-024)
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参考文献4

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共引文献89

同被引文献41

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