摘要
目的优选抗病毒口服液中广藿香、连翘、郁金、石菖蒲等4味药材挥发油最佳提取工艺。方法采用水蒸气蒸馏法提取挥发油,以收油率为指标,采用正交试验设计考察药材粒径、加水倍数、浸泡时间、提取时间等因素。结果最佳提取条件为:药材粉细段(<10 mm),加入8倍量水,浸泡3 h,提取6 h。结论优选得到的工艺稳定可行。
Objective To optimize the extraction procedure of essential oils from Herba Pogostemonis, Fructus Forsythiae, Radix curcumae and Rhizoma Acori Tatarinowii, four main components of Kangbingdu oral solution. Methods The essential oil was extracted by steam distillation. Orthogonal test was used to optimize extraction yield - related factors such as the grain size of the material, quantity of water, soaking time and extraction time. Chemical constituents of the extracted essential oil were identified by TLC. Results The optimized extraction conditions were as following: 10 mm or less in grain size, 8 times of water, three hours of immersion and six hours of distillation. Conclusion This optimized extraction process is stable and highly efficient.
出处
《广东药学院学报》
CAS
2007年第2期119-120,共2页
Academic Journal of Guangdong College of Pharmacy
关键词
广藿香
连翘
郁金
石菖蒲
挥发油
正交试验
Herba Pogostemonis
Fructus Forsythiae
Radix curcumae
Rhizoma Acori Tatarinowii
essential oil
orthogonal test