半胱胺对仔猪免疫机能的调节作用

Effect of Cysteamine on Immune Function in Piglets

在日粮中添加不同剂量半胱胺,研究半胱胺对仔猪免疫机能的影响。选用90头新生“杜×长×大”三元杂交仔猪,随机分为3组,每组30头,分别饲喂基础日粮、基础日粮+120 mg/kg半胱胺、基础日粮+200 mg/kg半胱胺。试验期为45 d。每窝随机选取20头仔猪,分别在14、24、32、45日龄进行前腔静脉采血,测定部分免疫指标。结果表明,日粮中添加半胱胺能显著提高仔猪体重、平均日增重,降低料重比;显著提高断奶后仔猪血清IgA、IgG含量及白细胞吞噬率和T-淋巴细胞转化率。添加120 mg/kg半胱胺的日粮有较好的促生长作用,而添加200 mg/kg半胱胺的日粮更能增强仔猪的免疫机能。试验结果显示,日粮中添加适量半胱胺,可有效抑制仔猪断奶应激,提高仔猪免疫力。

Different dosage of cysteamine（CS） were added to the basal diets to study the effect of CS on immunity in piglets. Ninety newborn ＂Duroc× Landrace× Yorkshire＂ crossbred piglets were divided into 3 groups with 30 piglets each,and fed with basal diet, basal diet plus 120 mg/kg CS and basal diet plus 200 mg/kg CS, respectively. The trial was conducted for 45 d. Blood samples in 20 piglets each group were taken on 14,24,32,42 day for measuring some immune indices. The results indicated that addition of cysteamine to the basal diet increased significantly the weight and average daily gain, decreased the ratio of feed to gain in piglets, increased significantly the levels of serum IgA,IgG, phagocytosis rates of neutral granular cells and conversion rates of T- lymphocytes. Basal diet with 120 mg/kg CS could improve growth performance more preferably, and with 200 mg/kg CS could enhance the immunity of piglets more significantly. The trial implied that appropriate dosage of CS could effectively inhibit weanling stress and enhance immunity of piglets.