猫眼视神经放射状切开术后视盘血管铸型研究

Experimental study on vascular cast after radial optic neaurotomy

目的利用血管铸型技术观察猫眼行视神经放射状切开术（RON）后视盘血管构筑的改变。方法健康成年家猫10只共20只眼，随机取单眼（共10只眼）行RON，对侧10只眼为正常对照。手术后90d20只眼均做树脂血管铸型标本，扫描电子显微镜下观察。结果正常对照组：视盘血供主要来源是睫状后短动脉、软膜动脉和睫状视网膜动脉，视盘周围的脉络膜毛细血管不参与筛板前区血供，未见视网膜中央血管系统和视神经周围完整的动脉环。手术组：手术切口处的视盘、视网膜血管和脉络膜毛细血管呈“V”型缺损，未造成视网膜大血管和脉络膜大血管层的损伤；未见切口处新生血管。结论RON可以造成视盘和周围局部组织的血管缺损，切口深度未达到秦氏环的解剖位置。

Objiective To observe the changes of angioarchitecture of the optic disc in cats eyes after radial optic neurotomy （RON）. Methods Ten healthy adult cats underwent unilateral RON randomly in 10 eyes as an operative group in this trial, and the fellow eyes （10 eyes） were as the control group. The colophony samples of vascular angioarchitecture of 20 eyes were made 90 days after RON and scanning electron microscope was used for the observation. Results In the control group, the blood supply of optic disc mainly came from the short posterior ciliary artery, pial artery, and retinal ciliary artery; the choroidal capillary vessels around the optic disc didn＇t take part in the blood supply in the anterior area; retinal central vascular system and complete arterial circle around the optic nerves were not seen. In the operative group, a V-shaped defect of the optic disc, retinal blood vessels and choroidal capillary vessels was found at the surgical incision; no injury of retinal blood vessels and choroidal large vascular layer was seen, and neovascularization at the incision were not found. Conclusions RON may cause the vascular defect of the optic disc and the peripheral local tissues. The depth of the incision doesn＇t reaeh the Zinn-Hallers circle.