摘要
约55％的急性髓细胞白血病（AML）患者存在克隆性的染色体异常，染色体改变已成为AML患者重要的预后指标。近年来，分子遗传学研究的进展使得大多数AML患者可以检出基因水平的异常，并为白血病的靶向治疗提供了新的目标。本文对此作一综述。
出处
《国际输血及血液学杂志》
CAS
2007年第3期222-226,共5页
International Journal of Blood Transfusion and Hematology
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