前列腺肉瘤的诊断与治疗

Diogonosis and treatment of sarcoma of the prostate(Report of 11 cases)

目的初步探讨前列腺肉瘤的诊断与治疗方法。方法回顾11例前列腺肉瘤患者的临床资料,并对所有患者进行随访。结果11例患者中,10例术前确诊前列腺肉瘤,1例手术后确诊。其中4例行根治性前列腺膀胱切除及回肠膀胱术,3例行前列腺切除术。2例行膀胱造瘘术,1例行放疗,1例仅行前列腺穿刺活检。病理结果:平滑肌肉瘤5例,横纹肌肉瘤4例,纤维肉瘤2例。1例失访,1例存活5年至今,1例术后8个月,尚未发现复发或转移,余8例均在确诊1年内死亡。结论前列腺肉瘤发展快,恶性度高,预后不良,应早期诊断,采用综合手段治疗。

Objective To study the diagnosis and treatment of prostatic sarcoma. Methods Eleven cases of prostatic sarcoma were reviewed retrospectively. All patients were followed-up. Results Of the 11 cases, 10 had accurate diagnosis preoperatively and 1 was diagnosed after operation. Four cases were treated with radical cystoprostatectomy and ileal conduit,3 cases were treated with prostatectomy,2cases with suprapubic cystostomy, 1 case with radiotherapy and 1 case with needle biopsy. Five were lieomyosareoma,4 rhabdomyosarcoma,and 2 fibrosarcoma. 1 case was lost to follow-up and lstill lives 5 years after operation. One case did not have recurrence or metastasis 8 months after operation. The others died within 1 year. Conclusions Sarcoma of the prostate is an aggressive and malignant tumor with poor prognosis. Early diagnosis and combined therapy should be adopted.