纳米羟基磷灰石/聚乳酸复合材料的性能测试

Performance testing of nano-hydroxyapatite/polylactic acid compound material

目的:测定纳米羟基磷灰石/聚乳酸复合材料的性能。方法:实验于2005-02/2006-08在兰州交通大学材料工程研究所实验室完成。基体材料采用荷兰普拉克生化公司生产的聚乳酸(Mr 400000)。增强材料采用纳米羟基磷灰石(自制)。聚乳酸在使用前进行纯化。纳米羟基磷灰石采用水热法合成。采用共混复合工艺制备不同纳米羟基磷灰石质量分数(0,0.05,0.10,0.15,0.20)的纳米羟基磷灰石/聚乳酸复合材料,并对其力学性能(弯曲强度、弯曲模量、剪切强度)和降解性能(降解速率)进行测试。结果:①力学性能:复合材料的弯曲强度随着纳米羟基磷灰石体积分数的增加而增大,在羟基磷灰石微粒的质量分数为0.15(体积分数为0.064)时弯曲强度出现峰值(153.6MPa),降解12周后复合材料弯曲强度仍有123.7MPa。复合材料的弯曲模量随着纳米羟基磷灰石体积分数的增加而增大,有一定的弯曲模量(5.7GPa),降解12周后复合材料弯曲模量为5.3GPa。复合材料的剪切强度随着纳米羟基磷灰石体积分数的增大呈下降趋势。②降解性能:随着降解时间的延长,复合材料的降解速率变化不大。结论:纳米羟基磷灰石/聚乳酸复合材料能满足松质骨的骨折内固定的力学性能要求。

AIM ： To determinate the performance of nano-hydroxyapatite （ n-HA ）/polylactic acid （ PLA ） compound material. METHODS： The experiment was completed in the Laboratory of Institute of Material and Engineering, Lanzhou Jiaotong University from February 2005 to August 2006. The substrate material used PLA produced by Dutch PURAC Biochemistry Company （Mr 400 000）. The enhancement material used the n-HA （self-restraint）. PLA was purified before it was used. The n-HA was synthesized with Wet-Hot method. Co-mixture of the compound craft preparation was applied to prepare n-HNPLA compound material of different n-HA mass fraction （0,0.05,0.10,0.15,0.20）. Its mechanics performance （bending strength, curving module, shearing strength） and the degeneration performance （degeneration speed） were tested. RESULTS： （1）Mechanics performance： The bending strength of compound material increased along with the volume fraction of n-HA. When the mass fraction of HA was 0.15 （volume fracture was 0.064）, the bending strength appeared the peak value （153.6 MPa）. After degraded for 12 weeks the bending strength of compound material still was 123.7 MPa. The curving module of compound material increased along with the volume fraction of n-HA, with the certain curving module （5.7 GPa）. After degraded for 12 weeks the curving module of compound material was 5.3 GPa. The shearing strength of compound material increased along with the volume fraction of n-HA, showing the drop tendency. （2）Degeneration performance： With the prolongation of degeneration, the degeneration speed of compound material changed slightly. CONCLUSION： The n-HNPLA compound material can meet the fixed mechanics performance requirement of alveolus fracture.