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脂联素与血管重塑的研究进展

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摘要 传统观念认为脂肪组织主要为体内被动的能量储存和释放器官,随着1994年脂肪激素瘦素(leptin)的发现.人们认识到血管周围脂肪细胞绝非仅仅起储存能量的作用.而是一活跃的内分泌代谢细胞,可以分泌和释放瘦素、脂联素(adiponectin,APN)、抵抗素(resistin)、肿瘤坏死因子α(TNF-α)、纤溶酶原激活物抑制物1(PAI-1)等20余种生物活性物质,统称为脂肪因子(adipokines)或者脂肪细胞因子(adipocytokines)。
出处 《内科理论与实践》 2007年第3期189-191,共3页 Journal of Internal Medicine Concepts & Practice
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