咳嗽变异性哮喘的中医证候学研究

TCM symptomatologic study on cough variant asthma

目的探讨咳嗽变异性哮喘患者的中医证候特点及演变规律。方法通过文献复习及相关研究资料的整合分析,筛选出咳嗽变异性哮喘临床常见到的62项症状及舌脉象,制定出统一的证候学科研观察表,对265例咳嗽变异性哮喘患者进行系统的临床观察与研究。结果初步总结出咳嗽变异性哮喘的核心症状及周边症状的特征性表现,并提出了以风邪犯肺为核心证型,其余5个基本证型(寒邪侵肺、热邪蕴肺、肝火犯肺、肺阴亏耗、肺气亏虚)可相互并见的证候学演变规律。结论风邪犯肺、肺失宣肃是致病的关键所在,疏风必须贯穿疾病治疗的始终。

Objective To investigate TCM syndrome characteristics and change laws in the patients with cough variant asthma （CVA）. Method Through the review and analysis of the relative documents and research materials there were 62 common symptoms and manifestations of tongue and pulse of CVA chosen in clinic, and an uniform observation table of symptomatology was established for the systematic observation and study on 265 patients with CVA. Result The chgracteristic manifestations of core symptoms and peripheral symptoms of CVA wore summed up primarily. The symptomatologic change laws were brought forward that the syndrome of wind evil attacking lung was the core syndrome type and other 5 basic syndrome types （syndrome of cold evil attacking lung, heat evil accumulating in lung, liver-fire attacking lung, consumption of lung-fin and deficiency of lung-qi） were intercurrent. Conclusion The syndrome of wind evil attacking lung and failure of lung in disseminating and purifying is the key of CVA onset, and the therapy of dispersing wind should be used from the beginning to the end of the treatment of CVA.