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EB病毒潜伏膜蛋白1与鼻咽癌 被引量:4

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摘要 鼻咽癌(nasopharyngeal carcinoma,NPC)为我国南方高发的上皮来源的肿瘤,其病因不清。大量研究表明,EB病毒(Epstein-Barr virus,EBV)编码的潜伏膜蛋白1(latent mem- brane protein 1,LMP1)是目前唯一被证实与细胞转化有关的具有癌基因功能的潜伏膜蛋白,通过干扰细胞内信号传导途径等发挥作用,促进鼻咽癌发生、发展和转移。本文旨在对EB病毒LMP1与鼻咽癌的发生发展研究现状做一综述。
出处 《国际耳鼻咽喉头颈外科杂志》 2007年第1期19-22,共4页 International Journal of Otolaryngology-Head and Neck Surgery
基金 重庆市卫生局重点项目(2003)和国家自然科学基金(30672311)联合资助.
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