心肌声学造影与冠状动脉造影的对比分析

Comparative Analysis of Myocardial Contrast Echocardiography and Coronary Angiography

目的:对比研究超声心肌声学造影(MCE)与冠状动脉造影(CAG)对冠心病的诊断价值。方法:静脉注射声学造影剂Brocco产的声诺维(Sonovue)进行超声二次谐波心肌声学显影,按ASE推荐左心室分析法,将左室壁分为16段进行心肌灌注记分,分值与冠状动脉狭窄程度比较分析。结果:MCE检出心肌灌注异常与冠状动脉狭窄≥50%的符合率为76%,当心肌灌注MCE分值为0时,相应冠状动脉狭窄>75%的可能性为80.8%,而MCE分值为1时,相应冠状动脉狭窄≤75%的可能性为81.8%,冠状动脉狭窄各组之间MCE分值差异有显著性,P值均<0.01～0.001。结论:MCE能较准确地反映心肌血流灌注,从而判断冠状动脉病变的程度和部位,可作为冠状动脉造影筛选的一个有效的方法。

Objective To compare the value of myocardial contrast echocardiography （MCE） and coronary angiography （CAG） for detecting coronary artery heart disease（CHD）, Methods The estimation of MCE score was made by visual analysis from 16 segment model of left ventricular walls according to coronary artery distribution. Comparison between MCE score and severity of coronary stenosis was made. Results When MCE score abnormity predicting, coronary artery, stenosis ≥50%, of diameter was 76%, when MCE score equals to 0,the possibility of correlated coronary stenosis 〉 75% was 80.8%, when MCE score equals 1, the possibility of correlated coronary stenosis ≤75% was 81.8%. There was significant difference between scores of different groups divided by severity of coronary stenosis （P 〈0. 01 -0. 001 ）, Conclusion MCE exactly reveals the myocardial perfusion,which helps to decide the severity and position of coronary stenosis. It can be an effective method to screen CAG candidates.