复方甘草酸苷治疗面部激素依赖性皮炎的疗效观察被引量：13

下载PDF

导出

摘要将70例临床确诊为激素依赖性皮炎的患者随机分为两组。实验组:复方甘草酸苷+左西替利嗪+维生素E乳膏;对照组:左西替利嗪+维生素E乳膏,用药后观察两组的丘疹、红斑、皮损面积、水肿、毛细血管扩张、瘙痒情况共6项指标。结果:实验组临床总有效率88.57%,较对照组65.71%效果明显,差异有显著性(P<0.01),未见明显的不良反应。复方甘草酸苷治疗面部激素依赖性皮炎是一种临床疗效较好,又安全的理想药物。

作者刘玉梅何婉苹何玉清张文君刘金花

机构地区广东省广州市皮肤病防治所

出处《中国麻风皮肤病杂志》 2007年第5期410-412,共3页 China Journal of Leprosy and Skin Diseases

关键词复方甘草酸苷激素依赖性皮炎疗效

分类号 R275 [医药卫生—中医皮科]

引文网络
相关文献

参考文献5

1中山秀夫.长期服用美能片为主治疗顽固性脱发的效果[日本][J].西日皮肤,2001,63:2-2.
2刘艳,宋方闻,胡毅文,袁静,马为民,周伯平.复方甘草甜素治疗慢性乙型肝炎临床疗效观察[J].中国药房,2002,13(7):420-421. 被引量：74
3宋方闻,白永敏,陈玉祥,曹阳,唐小平,李学俊,钟惟德.美能(β-甘草酸复方制剂)的分子构型及临床疗效[J].中国药房,2003,14(5):304-305. 被引量：141
4Kroes BH,Beukelman CJ,Vandenberg AJJ,et al.Inhibition of human complement by β-glycyrrhetimic acid.Immunology 1997;90:115.
5Mackenze MA.Tbe influence of glycyrrhetimic acid on liasma cortiol and cortisone in benlythy young volunteers.Clin Endocrino Metab 1990; 70:1637.

二级参考文献16

1Gold R. Mechnism of action of glucocorticosteroid hormones:possible implications for therapy of neuroimmunological disorders[J] .J Neuroimmunol, 2001,117: 8.
2Mackenze MA. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers[J]. J Clin Endocrinol Metab , 1990, 70:1637.
3Teruaki A. Inhibitory effects of glycyrrhetic acid derivatives on 11β-and 3α-hydroxysteroid dehydrogenases of rat liver[J].Chem Pharm Bull,1992,40(11):3021.
4Kroes BH, Beukelman CJ, Vandenberg AJJ, et al. Inhibition of human complement by β- glycyrrhetinic acid[J]. Immunology, 1997, 90:115.
5Kimura M, Inoue H, Hirabayashi K, et al. Glycyrrhizin and some analogues induce growth of primary cultured adult rat hepatocytes via epidermal growth factor receptors[J], Eur J Pharmacol , 2001,431:151.
6Tiziana Rossi, Rita Adriana Fano, Mario Castelli, et al. Correlation between high intake of glycyrrhizin and myolysis of the papillary muscles: an experimental in vivo study[J], Pharmacology & Toxicology, 1999, 85:221.
7Kazuhiko M. Efficacy of Stronger Neo - Minophagen C compared between two doses administered three times a week on patients with chronic viral hepatitis[J]. J of Gastroenterol Hepatol, 2002, 17:1198.
8Schemmer P. Intravenous glycine improves survival in rat liver transplantation[J] . Am J Physiol, 1999, 276:924.
9Wheeler MD, Ikejema, K, Enomoto N, et aL. Glycine : a new anti-inflammatory immunonutrient[J].Cell Mol Life Sci,1999,56:843.
10Kim K, Rhim T, Choi I, et al. N - acetylcysteine induces cell cycle arrest in hepatic stellate cells through its reducing activity[J]. J Biol Chem , 2001,276:40591.