真菌球性上颌窦炎术后黏膜恢复的观察

Recovery of the maxillary sinus mucosa after FESS

目的:观察真菌球性上颌窦炎患者术后黏膜恢复的过程,为术后处理提供参考。方法:68例鼻内镜术后定期随访,36例应用氟康唑冲洗术腔,32例应用生理盐水冲洗。结果:氟康唑组平均术腔清洁时间为1.58周,生理盐水组为1.63周。氟康唑组15例出现新生病变,生理盐水组16例出现。氟康唑组术腔完全上皮化时间为5.20周,生理盐水组为5.63周。三项对比,两组差异均无统计学意义(P>0.05)。结论:真菌球性上颌窦炎手术彻底清除病变后,至少要定期术腔处理6周,无需用抗真菌药行局部冲洗。

Objective： To investigate the recovery process of the maxillary mucosa after functional endoscopic sinus surgery （FESS） and provide information for the treatment after FESS. Methods： Sixty-eight cases were randomly divided into 2 groups： Miconazole was irrigated into the experimental group （36 cases） and normal saline （NS） was irri- gated into the control group （32 cases）. Results： In the experimental group, the mean cleaning time was 1.58 weeks, the mean epithelization time was 5.20 weeks, and new affections were found in 15 cases. In the NS group, the mean cleaning time was 1.63 weeks, the mean epithelization time was 5.63 weeks, and new affections were found in 16 cases. There were no differences between the two groups（ P 〉 0.05）. Conclusion： The cavities should be treated for 6 weeks at least and not be irrigated with drugs.