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骨髓基质细胞向神经细胞分化研究进展 被引量:3

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摘要 自2000年美国《科学》杂志首次报道来源于骨髓的细胞进入脑并表达神经表型以来,在动物模型上进行的骨髓基质细胞移植模拟治疗中风、脊髓损伤、肌萎缩性侧索硬化及帕金森病等的研究均显示有一定的疗效。近年来体外诱导骨髓基质细胞向神经系细胞分化的研究颇多,其中涉及到多种生物技术。该文就化合物诱导及潜在问题、蛋白及基因转染问题、骨髓基质细胞与神经细胞共培养等研究作一综述。
作者 严宁 侯铁胜
出处 《国际骨科学杂志》 2007年第3期183-185,202,共4页 International Journal of Orthopaedics
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