青年人肺癌195例临床分析

Clinical analysis of 195 young patients with lung cancer

目的探讨青年人肺癌临床病理特点。方法对1996年1月至2006年5月我院收治的资料较完整的195例40岁以下的原发性肺癌患者进行回顾性分析。结果青年人肺癌男女比例为1.71∶1,误诊率高达72.3%,病理类型以腺癌最多占(47.2%),其次为鳞癌(36.4%)及小细胞肺癌(5.1%),其它为未分化癌(11.3%)。TNM分期以Ⅲ、Ⅳ期居多占73.4%,手术切除率低。结论青年人肺癌误诊率高,病理类型以腺癌最多,女性发病率相对较高,确诊时多为晚期,预后差。重视青年患者的肺部表现,及时行相应检查,有助于肺癌的早期诊断及治疗。

Objective To evaluate the clinical and pathological characteristics of young lung cancer patients. Methods 195 young lung cancer patients （40 years old or younger） who had detailed clinical data were studied retrospectively. Results The occurrence ratio of male to female was 1.71 ： 1. Adenocarcinoma was accounted for 46. 8% and it was the main histological type of lung cancer in youth. The secondary was squamous carcinoma （36. 5% ）, followed by small cell lung cancer （4. 9% ）. The disease at advanced stage was most manifested （ about 73.4% ） in young patients. The rate of acceptable surgical resection was low. Conclusion Lung cancer in youth tends to be misdiagnosed. In these patients, adenoeareinoma is the main histological type and the disease at advanced stage is common. The prognosis is poor. It shold be paid more attention to the symptoms of chest while doing some essential examination so as to make the confirmation of the diagnosis and conduct reasonable treatment in early stage.