胸腔微创置管引流并糜蛋白酶治疗结核性胸腔积液

The pleural micro-wound drainage through a thin tube and the injection with chymotrypsin in the treatment of tuberculous pleural effusion

目的探讨胸腔微创置管引流并糜蛋白酶治疗结核性胸腔积液的疗效。方法患者在抗结核治疗条件下,将52例结核性胸腔积液患者随机分为治疗组(28例)对照组(24例),治疗组胸腔微创置管引流,并经引流管注入糜蛋白酶5mg。对照组行胸腔穿刺抽液。结果与对照组相比胸水消失时间明显缩短,胸膜粘连、肥厚发生率明显降低。结论胸腔微创置管引流并糜蛋白酶治疗结核性胸腔积液的方法安全,疗效明显,值得在临床上推广应用。

Objective To inquire into the curative effect of pleural micro-wound drainage through a thin tube and of chymotrypsin injection in the treatment of tuberculous pleural effusion. Methods Under the antituberculotic treatment, 52 patients of tuberculosis pleurisy were dividedrandomly into the treatment group （28 cases） and the control group （24 cases）. Pleural drainage in the treatment group was performed, using a thin tube with injection of 5mg chymotrypsin through the tube. The control group received thoracocentesis for draining effusion. Results Compare with the control group, the time of the chest liquid disappearing shortened significantly and the incidence rate of pleural thickening or adhension decreased apparently. Conclusions The pleural micro-wound drainage through a thin tube along with the injection with chymotrypsin in the treatment of tuberculous pleural effusion is a safe tharapy method. It has a satisfactory effect, which is worthy of being recommended for a wider use in clinical practice.