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毛细支气管炎并急性心功能不全患儿血清基质金属蛋白酶-9变化的意义 被引量:1

Changes of Matrix Metalloproteinase-9 in Bronchiolitis Combined with Acute Cardiac Insufficiency and Its Clinical Significance
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摘要 目的探讨毛细支气管炎并急性心功能不全患儿血清基质金属蛋白酶-9(MMP-9)的变化。方法对42例毛细支气管炎并急性心功能不全患儿和34例健康对照组儿童采用酶联免疫吸附试验和免疫斑点进行血清MMP-9及心肌肌钙蛋白I(cTnI)检测。结果毛细支气管炎并急性心功能不全患儿血清MMP-9水平及cTnI阳性率较健对照组明显升高(Pa<0.01),治疗后血清MMP-9水平及cTnI阳性率较治疗前明显下降(P<0.01,0.05)。二者水平呈明显正相关。结论MMP-9是毛细支气管炎并急性心功能不全患儿早期敏感、特异性指标;MMP-9与cTnI联合检测,能更好的反应毛细支气管炎并急性心功能不全患儿的心脏受损情况。
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2007年第10期770-770,787,共2页 Journal of Applied Clinical Pediatrics
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