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转化生长因子-β1/Smdas信号转导通路与糖尿病心肌病变 被引量：7

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摘要 转化生长因子-β1在糖尿病心肌病的发生发展过程中起着重要的调节作用,而Smads作为转化生长因子-β1受体胞内激活底物,除可介导转化生长因子-β1的信号转导外,还可介导非转化生长因子-β1途径的致心肌纤维化和心肌肥厚的信号转导。以转化生长因子-β1/Smads信号转导通路为治疗靶点,为防治糖尿病心肌病提供了新的思路。本文就这方面近来的研究进展作一综述。
作者 李龙英 肖谦
机构地区 重庆医学大学附属第一医院老年科
出处 《国外医学（老年医学分册）》 2007年第3期118-121,共4页 Foreign Medical Sciences(Geriatrics)
关键词 转化生长因子-Β1 SMAD 糖尿病心肌病
分类号 R587.2 [医药卫生—内分泌]
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参考文献20

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二级参考文献17

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共引文献11

同被引文献82

引证文献7

二级引证文献22

国外医学（老年医学分册）
2007年 第3期

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