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良性前列腺增生合并原发性高血压患者血管内皮功能变化的临床研究 被引量：4

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摘要 目的研究良性前列腺增生(BPH)合并原发性高血压(EH)患者血管内皮功能的变化,探讨血管内皮功能失调在BPH和EH两种疾病发病机制中的作用。方法检测BPH合并EH患者48例,BPH患者53例,男性EH患者40例和正常对照组(35名)的血浆内皮素1(ET-1)、一氧化氮(NO)、血管性假血友病因子(vWF)水平,应用二维超声测量肱动脉血流依赖性舒张功能(FMD),对其血管内皮功能进行评估,进行组间比较。结果与对照组相比,BPH合并EH组、BPH组和EH组ET-1、NO、vWF和FMD水平均有差异(P<0.01);BPH组和EH组间各指标差异无统计学意义;BPH合并EH组分别与BPH组和EH组相比,差异无统计学意义。结论BPH合并EH、BPH、EH3组患者均出现血管内皮功能受损,提示血管内皮功能失调是BPH及EH的共同发病机制之一。
作者 刘岩 宋月霞 王存龙
机构地区 河北医科大学附属唐山工人医院泌尿外科 华北煤炭医学院附属唐山市人民医院心内科
出处 《中华高血压杂志》 CAS CSCD 北大核心 2007年第5期419-420,共2页 Chinese Journal of Hypertension
关键词 良性前列腺增生 原发性高血压 血管内皮功能
分类号 R697.3 [医药卫生—泌尿科学] R544.1 [医药卫生—心血管疾病]
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参考文献10

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共引文献14

同被引文献26

引证文献4

二级引证文献15

中华高血压杂志
2007年 第5期

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