2Lee TT, Green BA. Advances in the management of acute spinal cord injury[J] . Orthop Clin North Am,2002,33 (2):311 - 315.
3Martin LJ, Liu Z. Injury-induced spinal motor neuron apoptosis is preceded By DNA single-strand Breaks and is p53-and Bax-dependent[J]. J NeuroBiol, 2002, 50(3): 181-197.
4Basso DM, Beattie MS, Bresnahan JC. A sensitive and reliable locomotor rating scale for open field testing in rats[J]. J Neurotrauma,1995,12(1): 1-21.
5Tikka T, Fiebich BL, Goldsteins G, et al. Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia[J]. J Neutosci,2001, 21(8): 2580-2588.
6Yrjanheikki J, Tikka T, Keinanen R, et al. A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window[J]. Proc Natl Acad Sci USA, 1999, 96: 13496-13500.
7Chen M, Ona VO, Li MW, et al. Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of huntington disease[J]. Nat Med, 2000, 6: 797-798.
8Brundula V, Rewcastle NB, Metz LM, et al. Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis[J]. Brain, 2002, 125: 1297-1308.
9Zhu S, Stavrovskaya I, Drozda M, et al. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice[J]. Nature, 2002, 417:74-78.
10Ferrer I, Lopez E, Blanco R, et al. Bcl-2, Bax, and bcl-x expression in the CA1 area of the hippocampus following transient forebrain ischemia in the adult gerbil[J]. Exp Brain Res, 1998,121(2):167-173.