1Barker AF,Couch L,Fiel TB,et al.Tobramycin solution for inhalation reduces sputum Pseudomonas aeruginosa density in bronchiectasis.Am J Respir Crit Care Med,2000,162:481-485.
2Ramsey BW,Pepe MS,Quan JM,et al.Intermittent administration of inhaled tobramycin in patients with cystic fibrosis.N Engl J Med,1999,340:23-30.
3Kuhn RJ.Formulation of aerosolized therapeutics.Chest,2001,120:94s-98s.
4Campbell PW 3rd,Saiman L.Use of aerosolized antibiotics in patients with cystic fibrosis.Chest,1999,116:775-788.
5Scheinberg P,Shore E.A pilot study of the safety and efficacy of tobramycin solution for inhalation in patients with severe bronchiectasis.Chest,2005,127:1420-1426.
6Falagas ME,Siempos Ⅱ,Bliziotis IA,et al.Administration of antibiotics via the respiratory tract for the prevention of ICU-acquired pneumonia:a meta-analysis of comparative trials.Crit Care,2006,10:R123.
