京沪两院精神病康复期患者用药品种比较

The comparison of the psychotropic Agents Administration for psychotic patients who were in rehabilitation between one psychiatric hospital in Beijing and another in Shanghai

目的:了解北京、上海两所精神病院康复期精神病患者的精神治疗药物状况。方法:采用一日法、自行编制的调查表对北京、上海两地病情稳定的190例住院精神病患者进行调查。结果:两地单一用药、联合用药比例总体上存在显著性差异(P<0.01);上海氯氮平使用比例较北京高(P<0.01),奋乃静使用比例较北京低(P<0.05);两地单一用药治疗方案中最常用的五种药物均是:氯氮平、氯丙嗪、奋乃静、利培酮、舒必利,上海氯氮平单一用药使用比例也高于北京(P<0.01);联合用药方案未存在明显差异(P>0.05)。结论:两所精神病院康复期精神病患者精神药物治疗部分存在差异,这种差异可能与两地医师用药习惯不同有关。

Objective： To learn the difference of the psychotropic agents for psychotic patients who were in rehabilitation between one psychiatric hospital in Beijing and another in Shanghai. Methods： 190 psychotic inpatients whose pathogenetic conditions were stable from two hospitals were investigated using the self-made questionnaire during the same day. Results： The two hospitals had significant difference in the ratios of mono-drug therapy, combined drugs therapy in total （P〈0.01）. The use ratio of clozapine in Shanghai higher than that in Beijing （P〈0.01）,while the use ratio of trilafon was lower （P〈0.05）.The most common five drugs in mono-drug therapy in both of the two hospitals were clozapine, chlorpromazine, trilafon, risperidone and sulpride, and the use ratio of clozapine in single psychotropic drug therapy was higher than that in Beijing（P〈0.01）.There were no significant difference in the kinds of combined drugs in the two hospitals（P〉0.05）. Conclusion： There existed part difference in the psychotropic drugs administration between the two hospitals, and that was probably related to prescribing habits of psychiatrists.