糖尿病病人颈动脉粥样硬化及相关性探讨

Relation between Diabetes Mellitus and Carotid Atherosclerosis

目的使用彩超检测2型糖尿病病人颈动脉粥样硬化,探讨二者之间的关系及相关性。方法对176例2型糖尿病和156例非糖尿病病人进行超声检查,观察双侧颈动脉内膜-中膜厚度(IMT)、斑块形成、狭窄程度变化。结果IMT随年龄增加而增厚(P<0.01),相同年龄段之间比较,糖尿病组较非糖尿病组增厚(P<0.01)。颈动脉粥样硬化斑块糖尿病组发生率均显著高于非糖尿病组(P<0.01),狭窄程度≥40%的发生率糖尿病组显著高于对照组(P<0.05)。结论通过观察颈动脉内膜-中膜厚度(IMT)和粥样斑块,可以判断2型糖尿病动脉硬化程度,预防并发症的发生。

Objective To study the relation between carotid atherosclerosis and diabetes. Methods The intima - media thickness （IMT）, the plaque and atheroma were measured in 176 patients （pts） with diabetes and 156 controls by CDFI. Results IMT thickened as the increase with age （P〈 0.01 ）. IMT in pts with diabetes was thicker than that in controls in same age group （P 〈0.01）. The number of carotid atherosclerosis plaque in pts with diabetes was more than that in controls （P〈0.01）. The incidences of cardio- eerebrovascular disease, hypertension, hyperlipemia and carotid plaque were significant difference in two groups （P 〈 0.05）. Conclusion The IMT of the great arteries and carotid plaque were related to the 2 type diabetes and they might be as a marker of atherosclerosis.