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A patient with spinal metastasis from hepatocellular carcinoma discovered from neurological findings 被引量:2

A patient with spinal metastasis from hepatocellular carcinoma discovered from neurological findings
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摘要 Although spinal tumors are uncommon, they may reduce survival or cause serious functional disorders in the extremities. Metastatic spinal tumors from malignant tumors can induce symptoms of spinal cord compression, such as paraplegia, quadriplegia, and vesicorectal disturbance, which are aggravated with progression of the diseases and time. We report a patient with hepatocellular carcinoma (HCC) who was suspected of having spinal lesions based on neurological findings, and a metastatic spinal tumor was found by imaging examination. Assuming that metastasis had occurred at the time lumbar pain developed, the patient reached the level of gait disturbance within only 4 mo, showing a rapid advancement of symptoms. If early diagnosis had been possible, treatment could be performed before acute myelopathy progressed to complete paralysis. We speculate that the terminal stage of HCC is not only liver failure associated with intrahepatic lesions but also metastasis to other regions, treatment for individual pathologies therefore, will be needed, which constitutes an important issue. Although spinal tumors are uncommon, they may reduce survival or cause serious functional disorders in the extremities. Metastatic spinal tumors from malignant tumors can induce symptoms of spinal cord compression, such as paraplegia, quadriplegia, and vesicorectal disturbance, which are aggravated with progression of the diseases and time. We report a patient with hepatocellular carcinoma (HCC) who was suspected of having spinal lesions based on neurological findings, and a metastatic spinal tumor was found by imaging examination. Assuming that metastasis had occurred at the time lumbar pain developed, the patient reached the level of gait disturbance within only 4 mo, showing a rapid advancement of symptoms. If early diagnosis had been possible, treatment could be performed before acute myelopathy progressed to complete paralysis. We speculate that the terminal stage of HCC is not only liver failure associated with intrahepatic lesions but also metastasis to other regions, treatment for individual pathologies therefore, will be needed, which constitutes an important issue.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第19期2758-2760,共3页 世界胃肠病学杂志(英文版)
关键词 肝细胞癌 脊髓转移 神经影像学检验 病例报告 Hepatocellular carcinoma Spinal cord metastasis Brain metastasis
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  • 1[1]Cho KB,Sohn JH,Park KB,Kwon DY,Lee YS,Hwang JS,Hur JW,Ahn SH,Park SK.laerum Kan Hakhoe Chi 2002; 8:218-222
  • 2[2]Kim M,Na DL,Park SH,Jeon BS,Roh JK.Nervous system involvement by metastatic hepatocellular carcinoma.J Neurooncol 1998; 36:85-90
  • 3[3]Friedman HD.Hepatocellular carcinoma with central nervous system metastasis:a case report and literature review.Med Pediatr Oncol 1991; 19:139-144
  • 4[4]Okamoto H,ShinkAl T,Matsuno Y,SAljo N.Intradural parenchymal involvement in the spinal subarachnoid space associated with primary lung cancer.Cancer 1993; 72:2583-2588
  • 5[5]Grem JL,Burgess J,Trump DL.Clinical features and natural history of intramedullary spinal cord metastasis.Cancer 1985;56:2305-2314
  • 6[6]Okuda K.Clinical aspects of hepatocellular carcinoma:Analysis of 134 cases.In Okuda K,Peters R,eds).Hepatocellular Carcinoma.New York:John Wiley & Sons,1976:387-436
  • 7[7]Brunner DR,Dunne MG,Rao KC,Sutherland JC,Cisternino SJ.Hepatoma presenting as a cerebellar metastasis.J Comput Tomogr 1982; 6:65-68
  • 8[8]Edelson RN,Deck MD,Posner JB.Intramedullary spinal cord metastases.Clinical and radiographic findings in nine cases.Neurology 1972; 22:1222-1231
  • 9[9]Van Goethem JW,van den Hauwe L,Ozsarlak O,De Schepper AM,Parizel PM.Spinal tumors.Eur J Radial 2004; 50:159-176
  • 10[10]Bilsky MH,Lis E,RAlzer J,Lee H,Boland P.The diagnosis and treatment of metastatic spinal tumor.Oncologist 1999; 4:459-469

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