性别因素在多器官功能障碍综合征中的意义

Importance of sexual factor in multiple organ dysfunction syndrome

目的探讨性别因素对多器官功能障碍综合征(MODS)发生及预后的影响。方法将173例MODS患者根据性别分为男性和女性两组,对两组患者的原发病、占同期ICU住院患者的比例及病死率进行比较。结果男性患者的原发病主要为多发创伤、严重感染、脑血管病及大手术,女性患者的原发病主要为严重感染、产科合并症、脑血管病、流行性出血热及中毒。同期ICU住院患者中,男性MODS患者所占比例明显高于女性,男性MODS患者病死率高于女性。年龄>55岁的男性、女性两组MODS患者病死率比较并无统计学意义。结论由于性别不同,MODS发生的原发病也不同。男性患者的MODS发生率及病死率高于女性患者,但与年龄有关。

Objective To investigate the influence of gender on multiple organ dysfunction syndrome （ MODS）. Methods 173 patients of MODS were divided into two groups according to gender, and the primary disease of MODS, the proportion of MODS in ICU patients of the corresponding period and the mortality were compared. Results The primary disease of male patients were multiple trauma, severe in- fection, cerebrovascular disease and major operation. The female patients＇primary diseases were severe infection, obstetrical complications, cerebrovascular disease, epidemic hemorrhagic fever and toxicosis. The proportion of male MODS in ICU patients of the corresponding period was higher than that of female pa- tients, and the mortality of male group was higher than that of female group too. The difference between two groups was little when patients＇age 〉 55. Conclusion The primary disease of MODS is different according to the gender, the incidence and the mortality of male group are higher than those of female group, but it＇s associated with age.