1例典型晚期乳腺癌癌细胞线粒体的形态参数的定量分析

The Stereologic and Image Analysis of Mtochondria About A Significant Carcinoma of Breast in Late

对1例典型乳腺硬性单纯癌癌细胞线粒体的7种形态参数进行体视学与图像分析,发现癌细胞与正常细胞比较,线粒体的表面积、周长、等效圆直径、体积密度、面数密度、比表面、表面积密度等7种形态参数有高度显著差异和显著差异。并讨论了乳腺癌癌细胞器——线粒体功能变异的定量依据。

In this article, sterologic method and image analysis was made on morphological parameters ot the simple carcinoma of breast cirrhosis. Compared with normal cells, sifnificant differences were found with 7 morphological parameters such as surface area, perimeter, diameter of equivalent round, volume density, numerical density on area and specific surface of mitochondria. Meanwhile, quantitative data were discussed about the dysfunction of mitochondria.