中心静脉与外周静脉置管在肿瘤化疗中的应用比较

Study on the application of central vein and peripheral catheterizations in the chemotherapy of malignant tumor

目的:观察中心静脉置管与外周静脉置管在恶性肿瘤患者化疗中的应用效果。方法:采用随机对照的研究方法,对71例恶性肿瘤患者随机分为两组:中心静脉置管组37例,外周静脉置管组34例。结果:中心静脉置管组一次性置管成功率为94.6%(35/37),外周静脉置管组一次性置管成功率为97.1%(33/34),P>0.05。中心静脉置管中位留管时间为91天,外周静脉置管中位留管时间为5天,P<0.001。中心静脉置管组没有1例发生化疗所致栓塞性静脉炎及药物外渗,而外周静脉置管组则有64.7%的病例发生化疗所致药物性静脉炎及药物外渗。结论:中心静脉置管安全、可长期保留,在肿瘤病人的化疗、抢救和高营养治疗中有较高的临床价值,提高了肿瘤病人的生存质量,值得推广使用。

Objective：To investigate the application of central vein and peripheral vein catheterizations in the chemotherapy of malignant tumor. Methods：seventy-one patients were randomly divided into two groups, central vein catheterization group （37 cases）and peripheral vein catheterization group （34 cases）. Results：The achievement rate of one time puncture for central vein catheterization group was 94.6 %and that for the other group was 97.1%, （P〉0.05）. Medium time of keeping catheter in the first group were 91 days and the second 5 days （P〈0.001）. The infection or embolism was not found in the first group ,but 64.7% cases were found in the second group. Conclusions：The central vein catheter was safe and could be kept for long time. This catheterizations had higher clinical value on the chemotherapy intensive care and high-nutrition cure of patients with tumor, and improved the life quality of patients, which is quite worthy of popularization.