70例45岁以下自发性脑出血患者的回顾性分析

Retrospective study of 70 cases of SICH under the age of 45

目的：探讨45岁以下自发性脑出血（SICH）病人的危险因素、临床及生化特点.方法：回顾性分析70例SICH患者的危险因素及临床表现.结果：危险因素：高血压28例（40%）,经常吸烟19例（27%）,长期饮酒14例（20%）.出血部位：基底节区36例（51%,左侧19例、右侧17例）,脑叶19例（27%）,脑干7例（10%）,脑室3例（4%）,小脑1例（1%）,多灶4例（6%）,破入脑室10例（14%）.57例（81%）预后良好,死亡8例.30例中有7例（23%）TC≤4.128mmol/L.血WBC≥10 × 109/L者平均住院日较WBC＜10×109/L者明显延长.12例（17%）WBC＞20×109/L者预后差.结论：45岁以下人群脑出血的危险因素主要与高血压、吸炯和长期饮酒有关 出血部位以基底节区多见.TC降低可能与年轻人脑出血有关.血WBC计数对预后评价有帮助.

Objective：To study the risk factors and the clinical and biochemical features of the patients under the age of 45 suffering from spontaneous intracerebral hemorrhage （SICH）. Methods：The risk factors and clinical manifestation of 70 cases of SICH were studied retrospectively. Results：The risk factors included hypertension （28cases,40%）, regular smoking（19cases, 27%）, long-term alcohol drinking（14cases , 20% ）.The bleeding location was basal ganglia area（36cases,51%, 19 cases on left side and 17cases on right side）, lobar （ 19cases, 27% ）, brain stem （7cases, 10% ）, ventricles （3cases, 4% ）, cerebellum （ 1 case, 1% ）, muhi-foci（4cases,6%）. There were 10 cases bleeding into ventricles（14%）. 57cases（ 81% ）had good pronosis,8 cases died.There were 7 cases （among 30cases） who the TC level were less than 4.128mmol/LThe average hospitalization days of those with WBC≥10 ×10^9/L were longer than that with WBC≥10 ×10^9/L. 12 cases（17%） with WBC≥20 × 10^9/L, had poor prognosis. Conclusion：Risk factors of patients of SICH under the age of 45 are hypertension, smoking and long-term alcohol drinking.Basal ganglion is the most common bleeding location.Low TC level tends to may be a risk factor of young patients.WBC counting can help evaluate the prognosis.