中药通脉饮治疗上肢无脉症及其对血流动力学参数的影响

Clinical Assessment of TongMaiYin Decoction on Pulseless Disease in Upper Limbs and Ultrasound Hemodynamics Study

目的:观察中药通脉饮治疗上肢无脉症的疗效,及其对无脉症患者彩色多普勒血流显像及频谱多普勒,尤其是血流动力学参数的影响。方法:采用自拟中药通脉饮治疗上肢无脉症患者35例,评估其临床疗效,同时采用HP-5500型Acuson-128xp/10 A.R.TCDFI诊断仪检测,并记录相关数值。结果:治疗后临床症状明显改善,总有效率为85.7%。经超声检测患肢狭窄远端肱动脉PSV值明显上升(治疗前为37.94±2.98cm/s,治疗后为40.15±2.62cm/s,P<0.01)。结论:中药通脉饮可以有效改善无脉症患者的上肢缺血症状,增加患肢远端血流速度。超声检查可以提供形态学和血流动力学信息,可以作为疗效评估的客观指标之一。

Objective： To assessment the clinical effect of TongMaiYin decoction （TMY） on pulseless disease in upper limbs and investigates the ultrasonographic characters of the pulseless disease by color Doppler ultrasound, especially the hemodynamics characters. Methods： Thirty - five patients suffering from pulseless disease were treated with TMY. The changes of clinical symptoms were observed, the presence of flow and compressibility was assessed with duplex ultrasound scanning. Results： The clinical symptoms were improved markedly and after treatment there was significant difference in the PSV of brachial artery. Conclusion ： TMY was effective in treating pulseless disease and it could improve the PSV in brachial artery significantly. Ultrasonography was one of the indexes, which could be used to evaluate of effect of pulseless disease.