藏药川西小黄菊化学成分的研究

Chemical Constituents from Pyrethrum tatsienense

目的:对藏药川西小黄菊(Pyrethrum tatsienense)全草化学成分进行分离鉴定。方法:利用普通硅胶柱色谱和制备薄层色谱等方法进行分离、纯化,并经超导核磁共振、质谱等现代波谱技术确定其结构。结果:从川西小黄菊的乙醇(95%)室温提取物中获得6个化合物,其结构被确定为:三十烷(1),亚油酸(2),松脂素(3),松脂素-4’-O-β-D-葡萄糖苷(4),betulabuside A(5),二氢丁香苷(6)。结论:这6个化合物均为首次从该植物中分离得到。

Objective ： To isolate and identify the chemical constituents from the whole plant of Pyrethrum tatsienense, which has been used as traditonal herb medicine in the treatment of some diseases. Methods：The compounds were isolated by column chromatography and their structures were elucidated through spectroscopic analysis （NMR）. Results：Six compounds were isolated and identified as ： linoeic acid,pinoresinol, （ ＋ ）-pinoresinol-4＇-O-β-D- glucopyranoside, betulabuside A, dihydrosyringin. Conclusion：All these compounds were obtained from Pyrethrum tatsienense for the first time.