白花丹化学成分的研究

Chemical Constituents from Aerial Parts of Plumbago zeylanica Linn.

目的:研究白花丹Plumbago zeylanicaLinn.地上部分的化学成分。方法:对白花丹95%乙醇提取物的乙酸乙酯部分进行色谱分离,通过理化性质和波谱分析鉴定化合物的结构。结果:从白花丹中分离得到9个化合物,分别鉴定为白花丹醌(Ⅰ),isoshinanolone(Ⅱ),白花丹酸(Ⅲ),β-谷甾醇(Ⅳ),对羟基苯甲醛(Ⅴ),反式桂皮酸(Ⅵ),香兰子酸(Ⅶ),2,5-二甲基-7-羟基-色原酮(Ⅷ),3-吲哚甲醛(Ⅸ)。结论:化合物Ⅴ,Ⅶ,Ⅷ和Ⅸ为首次从白花丹属植物中分离得到。

Objective ： To investigate the chemical constituents of the aerial parts of Plumbago zeylanica Linn. Methods ： The constituents of the EtOAc-soluble portion in the 95% ethanol extract were isolated and purified by means of chromatography. Compounds were identified by their physical characteristics and spectral features. Results： Nine compounds were isolated as plumbagin （ Ⅰ ） , isoshinanolone （ Ⅱ ） , plumbagic acid （ Ⅲ ） , β-sitosterol （ Ⅳ ） ,4-hydroxybenzaldehyde （ Ⅴ ） , trans-cinnamic acid （ Ⅵ ） , vanillic acid （ Ⅶ ） , 2, 5-dimethyl-7-hydroxychromone （ Ⅷ ） , indole-3-earboxaldehyde （ Ⅸ ）. Conclusion ： Compounds Ⅴ,Ⅶ,Ⅷ, and Ⅸ were isolated for the first time from Plumbago Linn.